Telbivudine protects infants
نویسندگان
چکیده
منابع مشابه
Safety evaluation of telbivudine.
IMPORTANCE OF THE FIELD Successful treatment of chronic hepatitis B (CHB) often requires long-term oral nucleoside/nucleotide agents which can be associated with viral resistance, patient non-compliance and adverse effects. Telbivudine is one of the more potent options available, with a 6.5- to 6.6-log copies/ml hepatitis B DNA reduction at 12 weeks in an early viral kinetic study, a potency co...
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BACKGROUND Chronic arsenic exposure causes a wide range of health effects, but little is known about critical windows of exposure. Arsenic readily crosses the placenta, but the few available data on postnatal exposure to arsenic via breast milk are not conclusive. AIM Our goal was to assess the arsenic exposure through breast milk in Bangladeshi infants, living in an area with high prevalence...
متن کاملMaternal preeclampsia protects preterm infants against severe retinopathy of prematurity.
OBJECTIVE To study the influence of maternal preeclampsia on the occurrence of retinopathy of prematurity. STUDY DESIGN A prospective cohort study of 324 preterm neonates with birth weight ≤ 1500 g and gestational age ≤ 32 weeks. Multiple maternal and perinatal factors were analyzed for association and confounding by multiple logistic regression analysis. RESULTS Mean birth weight was 1128 ...
متن کاملClinicopathological Features of Telbivudine-Associated Myopathy
Telbivudine, a thymidine nucleoside analog, is a common therapeutic option for chronic hepatitis B infection. While raised serum creatine kinase is common, myopathy associated with telbivudine is rare. Reports on its myopathological features are few and immunohistochemical analyses of inflammatory cell infiltrates have not been previously described. We describe the clinical, myopathological and...
متن کاملTelbivudine prevents vertical transmission of hepatitis B virus from women with high viral loads: a prospective long-term study.
BACKGROUND & AIMS Hepatitis B virus (HBV) infection is a leading cause of liver diseases. We investigated the efficacy and safety of telbivudine in preventing transmission of HBV from hepatitis B e antigen-positive pregnant women with high viral loads to their infants in an open-label study. METHODS We performed a prospective study of 450 hepatitis B e antigen-positive pregnant women with HBV...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2012
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2012.43